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2008-11-27Zeitschriftenartikel DOI: 10.1515/JPM.2009.063
Flowcytometric assessment of fetomaternal hemorrhage during external cephalic version at term
dc.contributor.authorScholz, Christoph
dc.contributor.authorKachler, Andrea
dc.contributor.authorHermann, Christine
dc.contributor.authorWeissenbacher, Tobias
dc.contributor.authorToth, Bettina
dc.contributor.authorFriese, Klaus
dc.contributor.authorKainer, Franz
dc.date.accessioned2017-06-17T10:34:10Z
dc.date.available2017-06-17T10:34:10Z
dc.date.created2010-07-01
dc.date.issued2008-11-27
dc.identifier.issn1619-3997
dc.identifier.urihttp://edoc.hu-berlin.de/18452/12786
dc.description.abstractExternal cephalic version (ECV) at term is a safe procedure and reduces the incidence of cesarean sections for breech presentation. One of the known complications, however, is an ECV-related disruption of the placental barrier and a subsequent transfusion of fetal blood into maternal circulation. While the incidence of ECV-related fetomaternal hemorrhage (FMH) has been determined recently in a large trial using a manual Kleihauer-Betke test (KBT), questions remain on the amount of ECV-related FMH. KBT, which detects fetal red blood cells (RBC) on the basis of acidic resistance of fetal hemoglobin (HbF), is known to be a sensitive test, yet prone to procedural errors limiting its accuracy in quantifying FMH. In this study we investigated 50 patients for FMH before and after ECV, using a dual-color flow cytometric test kit with a lower limit of quantification of 0.05% fetal RBC in maternal peripheral blood. Three patients had a quantifiable increase of fetal RBC detected after ECV (0.06%; 0.08%; 0.1%). None of these subtle increments was predictable by ECV-related clinical parameters or translated into fetal compromise. Using a sensitive and accurate flow cytometric test method, our data provide further assurance to mothers on the safety of ECV at term.eng
dc.language.isound
dc.publisherKooperation de Gruyter
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/
dc.titleFlowcytometric assessment of fetomaternal hemorrhage during external cephalic version at term
dc.typearticle
dc.identifier.urnurn:nbn:de:kobv:11-100153896
dc.identifier.doi10.1515/JPM.2009.063
dc.identifier.doihttp://dx.doi.org/10.18452/12134
local.edoc.container-titleJournal of Perinatal Medicine
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-publisher-namede Gruyter
local.edoc.container-volume37
local.edoc.container-issue4
local.edoc.container-year2009
local.edoc.container-firstpage334
local.edoc.container-lastpage337
dc.description.versionPeer Reviewed

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