2009-01-26Zeitschriftenartikel DOI: 10.1515/JPM.2009.070
Oxygen saturation in healthy newborns; influence of birth weight and mode of delivery
Aims: To study the normal levels of oxygen saturation (SpO2) in healthy newborns during the first 24 h of life and the possible relationship to birth weight and mode of delivery. Methods: SpO2 was measured by pulse oximetry on one occasion between 2 and 24 h after birth in 6805 asymptomatic newborns with gestational age ≥34 weeks and birth weight ≥2500 g. Results: The average SpO2 for all children was 98.0% (SD 1.4). SpO2 was negatively related to birth weight and ranged from 98.2% (1.4) in children with birth weight 2750–2999 g to 97.6% (1.3) in children weighing >4500 g (P<0.001). No relationship exists between SpO2 and gestational age or gender when correcting for birth weight. SpO2 was independently related to mode of delivery, with higher levels in children born by cesarean section (98.3%; 1.3) than by vaginal delivery (98.0; 1.4; P<0.001). There was no relationship between SpO2 and the interval from delivery to measurement. Conclusions: In healthy newborns, levels of SpO2 measured between 2 and 24 h of life are negatively related to birth weight and related to mode of delivery. However, the variation was within a small range and probably has few implications for the routine use of SpO2 in newborns.