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2009-01-29Zeitschriftenartikel DOI: 10.1515/JPM.2009.075
The effect of bilateral pelvic neurectomy on uterine and abdominal electrical and pressure activity, as measured by telemetry in conscious, unrestrained pregnant rats
dc.contributor.authorMackay, Lynnette B.
dc.contributor.authorGarfield, Robert E.
dc.contributor.authorManer, William L.
dc.date.accessioned2017-06-17T10:35:19Z
dc.date.available2017-06-17T10:35:19Z
dc.date.created2010-07-01
dc.date.issued2009-01-29
dc.identifier.issn1619-3997
dc.identifier.urihttp://edoc.hu-berlin.de/18452/12792
dc.description.abstractAims: Bilateral pelvic neurectomy (BPN) interferes with delivery in rats. This work measures the effect of BPN on uterine and abdominal electromyography (EMG) and pressure during gestation and delivery. Methods: Uterine EMG and intra-uterine pressure (IUP), as well as abdominal muscle EMG and intra-abdominal pressure (IAP), were recorded on days 19–24 in rats. Mean values were determined for the peak frequency of the power density spectrum (PDS) of the uterine and abdominal EMG “bursts,” the integral of the abdominal EMG power spectrum (IPS), and the area under the IUP and IAP curves (AUIUP and AUIAP). Results: Uterine EMG power density spectrum peak frequency and AUIUP were low during days 19–21 in all rats, and on days 22–23 increased sharply and significantly in both groups. Before delivery, sham rat recordings showed sudden sharp increases in AUIAP, AUIUP and IPS as “pushing” was observed. Pushing was not observed or recorded in laboring BPN rats and they did not deliver normally. Conclusions: A functional pelvic nerve is required for normal labor and delivery in rats. BPN inhibits abdominal EMG and contractions necessary to expel the fetus.eng
dc.language.isound
dc.publisherKooperation de Gruyter
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/
dc.titleThe effect of bilateral pelvic neurectomy on uterine and abdominal electrical and pressure activity, as measured by telemetry in conscious, unrestrained pregnant rats
dc.typearticle
dc.identifier.urnurn:nbn:de:kobv:11-100153952
dc.identifier.doi10.1515/JPM.2009.075
dc.identifier.doihttp://dx.doi.org/10.18452/12140
local.edoc.container-titleJournal of Perinatal Medicine
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-publisher-namede Gruyter
local.edoc.container-volume37
local.edoc.container-issue4
local.edoc.container-year2009
local.edoc.container-firstpage313
local.edoc.container-lastpage319
dc.description.versionPeer Reviewed

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