1981-01-01Zeitschriftenartikel DOI: 10.1515/cclm.19184.108.40.2069
Evolution of Clinical Enzymology
The evolution of clinical enzymology is discussed in relation to the history of general enzymology and clinical chemistry. The discussion is limited to the period from 1835 (definition of catalysis by Berzelius) to 1935 (description of the optical test by Warburg). In conclusion, a general account is given of the introduction of the concept of quantitative enzyme activity determination into clinical medicine.
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