1997-01-01Zeitschriftenartikel DOI: 10.1515/cclm.19188.8.131.523
Measurement of Free Triiodothyronine in Intensive Care Patients
Comparison of Two Routine Methods
One hundred sera from intensive care patients, and 93 sera from endocrinological outpatients were used for a comparison between two automated assays for free triiodothyronine (Enzymun Test, and Elecsys 2010, both Boehringer Mannheim, Mannheim, Germany). In outpatients a good correlation between both methods was found (r=0.932). In contrast, comparability between the two assays was poor in intensive care patients (r=0.75, after exclusion of two outliers); significantly more values in the hypothyroid range were found with the Elecsys 2010 assay (n=83, compared with n=33 with the Enzymun Test; x2 test p=0.001). We conclude that routine measurement of free triiodothyronine which has the theoretical advantage of quantifying the biologically active fraction of thyroid hormones may have methodological limitations in severely ill patients.
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