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2020-09-03Zeitschriftenartikel DOI: 10.3389/fphys.2020.01053
Influence of Delayed Conductance on Neuronal Synchronization
dc.contributor.authorProtachevicz, Paulo R.
dc.contributor.authorBorges, Fernando S.
dc.contributor.authorIarosz, Kelly C.
dc.contributor.authorBaptista, Murilo S.
dc.contributor.authorLameu, Ewandson L.
dc.contributor.authorHansen, Matheus
dc.contributor.authorCaldas, Iberê L.
dc.contributor.authorSzezech, José D.
dc.contributor.authorBatista, Antonio M.
dc.contributor.authorKurths, Jürgen
dc.date.accessioned2020-09-25T08:17:30Z
dc.date.available2020-09-25T08:17:30Z
dc.date.issued2020-09-03none
dc.date.updated2020-09-03T10:00:06Z
dc.identifier.urihttp://edoc.hu-berlin.de/18452/22656
dc.description.abstractIn the brain, the excitation-inhibition balance prevents abnormal synchronous behavior. However, known synaptic conductance intensity can be insufficient to account for the undesired synchronization. Due to this fact, we consider time delay in excitatory and inhibitory conductances and study its effect on the neuronal synchronization. In this work, we build a neuronal network composed of adaptive integrate-and-fire neurons coupled by means of delayed conductances. We observe that the time delay in the excitatory and inhibitory conductivities can alter both the state of the collective behavior (synchronous or desynchronous) and its type (spike or burst). For the weak coupling regime, we find that synchronization appears associated with neurons behaving with extremes highest and lowest mean firing frequency, in contrast to when desynchronization is present when neurons do not exhibit extreme values for the firing frequency. Synchronization can also be characterized by neurons presenting either the highest or the lowest levels in the mean synaptic current. For the strong coupling, synchronous burst activities can occur for delays in the inhibitory conductivity. For approximately equal-length delays in the excitatory and inhibitory conductances, desynchronous spikes activities are identified for both weak and strong coupling regimes. Therefore, our results show that not only the conductance intensity, but also short delays in the inhibitory conductance are relevant to avoid abnormal neuronal synchronization.eng
dc.language.isoengnone
dc.publisherHumboldt-Universität zu Berlin
dc.rights(CC BY 4.0) Attribution 4.0 Internationalger
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectsynchronizationeng
dc.subjectintegrate-and-fireeng
dc.subjectneuronal networkeng
dc.subjecttime delayeng
dc.subjectconductanceeng
dc.subject.ddc610 Medizin und Gesundheitnone
dc.titleInfluence of Delayed Conductance on Neuronal Synchronizationnone
dc.typearticle
dc.identifier.urnurn:nbn:de:kobv:11-110-18452/22656-9
dc.identifier.doi10.3389/fphys.2020.01053none
dc.identifier.doihttp://dx.doi.org/10.18452/21973
dc.type.versionpublishedVersionnone
local.edoc.container-titleFrontiers in Physiologynone
local.edoc.pages9none
local.edoc.type-nameZeitschriftenartikel
local.edoc.institutionMathematisch-Naturwissenschaftliche Fakultätnone
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-publisher-nameFrontiers Media S.A.none
local.edoc.container-publisher-placeLausannenone
local.edoc.container-volume11none
dc.description.versionPeer Reviewednone
local.edoc.container-articlenumber1053none
dc.identifier.eissn1664-042X
local.edoc.affiliationProtachevicz, Paulo R.; Instituto de Física, Universidade de São Paulo, São Paulo, Brazilnone
local.edoc.affiliationBorges, Fernando S.; Center for Mathematics, Computation, and Cognition, Federal University of ABC, São Paulo, Brazilnone
local.edoc.affiliationIarosz, Kelly C.; Instituto de Física, Universidade de São Paulo, São Paulo, Brazilnone
local.edoc.affiliationBaptista, Murilo S.; Institute for Complex Systems and Mathematical Biology, SUPA, University of Aberdeen, Aberdeen, United Kingdomnone
local.edoc.affiliationLameu, Ewandson L.; Cell Biology and Anatomy Department, University of Calgary, Calgary, AB, Canadanone
local.edoc.affiliationHansen, Matheus; Graduate Program in Science–Physics, State University of Ponta Grossa, Ponta Grossa, Brazilnone
local.edoc.affiliationCaldas, Iberê L.; Instituto de Física, Universidade de São Paulo, São Paulo, Brazilnone
local.edoc.affiliationSzezech, José D.; Graduate Program in Science–Physics, State University of Ponta Grossa, Ponta Grossa, Brazilnone
local.edoc.affiliationBatista, Antonio M.; Instituto de Física, Universidade de São Paulo, São Paulo, Brazilnone
local.edoc.affiliationKurths, Jürgen; Department of Physics, Humboldt University, Berlin, Germanynone

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