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2020-07-13Zeitschriftenartikel DOI: 10.18452/22171
Play, but not observing play, engages rat medial prefrontal cortex
dc.contributor.authorConcha-Miranda, Miguel
dc.contributor.authorHartmann, Konstantin
dc.contributor.authorReinhold, Annika
dc.contributor.authorBrecht, Michael
dc.contributor.authorSanguinetti-Scheck, Juan Ignacio
dc.date.accessioned2020-11-20T10:24:00Z
dc.date.available2020-11-20T10:24:00Z
dc.date.issued2020-07-13none
dc.identifier.other10.1111/ejn.14908
dc.identifier.urihttp://edoc.hu-berlin.de/18452/22796
dc.description.abstractRats have elaborate cognitive capacities for playing Hide & Seek. Playing Hide & Seek strongly engages medial prefrontal cortex and the activity of prefrontal cortex neurons reflects the structure of the game. We wondered if prefrontal neurons would also show a mirroring of play‐related neural activity. Specifically, we asked how does the activity in the rat medial prefrontal cortex differ when the animal plays itself versus when it observes others playing. Consistent with our previous work, when the animal plays itself we observed medial prefrontal cortex activity that was sharply locked to game events. Observing play, however, did not lead to a comparable activation of rat medial prefrontal cortex. Firing rates during observing play were lower than during real play. The modulation of responses in medial prefrontal cortex by game events was strong during playing Hide & Seek, but weak during observing Hide & Seek. We conclude the rat prefrontal cortex does not mirror play events under our experimental conditions.eng
dc.language.isoengnone
dc.publisherHumboldt-Universität zu Berlin
dc.rights(CC BY 4.0) Attribution 4.0 Internationalger
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectgameeng
dc.subjectmirror neuronseng
dc.subjecthide & seekeng
dc.subjectsingle uniteng
dc.subjectsocialeng
dc.subject.ddc610 Medizin und Gesundheitnone
dc.titlePlay, but not observing play, engages rat medial prefrontal cortexnone
dc.typearticle
dc.identifier.urnurn:nbn:de:kobv:11-110-18452/22796-1
dc.identifier.doihttp://dx.doi.org/10.18452/22171
dc.type.versionpublishedVersionnone
local.edoc.container-titleEuropean journal of neurosciencenone
local.edoc.pages13none
local.edoc.type-nameZeitschriftenartikel
local.edoc.institutionCluster im Rahmen der Exzellenzinitiativenone
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-publisher-nameWileynone
local.edoc.container-publisher-placeOxford [u.a.]none
local.edoc.container-volume52none
local.edoc.container-issue9none
local.edoc.container-firstpage4127none
local.edoc.container-lastpage4138none
dc.description.versionPeer Reviewednone
dc.identifier.eissn1460-9568

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