Cyanobacteria—From the Oceans to the Potential Biotechnological and Biomedical Applications
dc.contributor.author | Khalifa, Shaden A. M. | |
dc.contributor.author | Shedid, Eslam S. | |
dc.contributor.author | M. Saied, Essa | |
dc.contributor.author | Jassbi, Amir Reza | |
dc.contributor.author | Jamebozorgi, Fatemeh H. | |
dc.contributor.author | Rateb, Mostafa E. | |
dc.contributor.author | Du, Ming | |
dc.contributor.author | Abdel-Daim, Mohamed M. | |
dc.contributor.author | Kai, Guo-Yin | |
dc.contributor.author | Al-Hammady, Montaser A. M. | |
dc.contributor.author | Xiao, Jianbo | |
dc.contributor.author | Guo, Zhiming | |
dc.contributor.author | El-Seedi, Hesham R. | |
dc.date.accessioned | 2021-10-27T07:29:38Z | |
dc.date.available | 2021-10-27T07:29:38Z | |
dc.date.issued | 2021-04-24 | none |
dc.date.updated | 2021-05-03T18:10:37Z | |
dc.identifier.uri | http://edoc.hu-berlin.de/18452/24267 | |
dc.description.abstract | Cyanobacteria are photosynthetic prokaryotic organisms which represent a significantsource of novel, bioactive, secondary metabolites, and they are also considered an abundant source ofbioactive compounds/drugs, such as dolastatin, cryptophycin 1, curacin toyocamycin, phytoalexin,cyanovirin-N and phycocyanin. Some of these compounds have displayed promising results insuccessful Phase I, II, III and IV clinical trials. Additionally, the cyanobacterial compounds applied tomedical research have demonstrated an exciting future with great potential to be developed into newmedicines. Most of these compounds have exhibited strong pharmacological activities, includingneurotoxicity, cytotoxicity and antiviral activity against HCMV, HSV-1, HHV-6 and HIV-1, so thesemetabolites could be promising candidates for COVID-19 treatment. Therefore, the effective large-scale production of natural marine products through synthesis is important for resolving the existingissues associated with chemical isolation, including small yields, and may be necessary to betterinvestigate their biological activities. Herein, we highlight the total synthesized and stereochemicaldeterminations of the cyanobacterial bioactive compounds. Furthermore, this review primarilyfocuses on the biotechnological applications of cyanobacteria, including applications as cosmetics,food supplements, and the nanobiotechnological applications of cyanobacterial bioactive compoundsin potential medicinal applications for various human diseases are discussed. | eng |
dc.description.sponsorship | Stockholm University | |
dc.language.iso | eng | none |
dc.publisher | Humboldt-Universität zu Berlin | |
dc.rights | (CC BY 4.0) Attribution 4.0 International | ger |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
dc.subject | cyanobacteria | eng |
dc.subject | clinical trials | eng |
dc.subject | antioxidant | eng |
dc.subject | antiviral | eng |
dc.subject | COVID-19 | eng |
dc.subject | dietary supplements | eng |
dc.subject | biotechnological applications | eng |
dc.subject | total synthesis | eng |
dc.subject.ddc | 540 Chemie und zugeordnete Wissenschaften | none |
dc.subject.ddc | 610 Medizin und Gesundheit | none |
dc.title | Cyanobacteria—From the Oceans to the Potential Biotechnological and Biomedical Applications | none |
dc.type | article | |
dc.identifier.urn | urn:nbn:de:kobv:11-110-18452/24267-9 | |
dc.identifier.doi | http://dx.doi.org/10.18452/23609 | |
dc.type.version | publishedVersion | none |
local.edoc.pages | 35 | none |
local.edoc.type-name | Zeitschriftenartikel | |
local.edoc.container-type | periodical | |
local.edoc.container-type-name | Zeitschrift | |
dc.description.version | Peer Reviewed | none |
dc.identifier.eissn | 1660-3397 | |
dcterms.bibliographicCitation.doi | 10.3390/md19050241 | none |
dcterms.bibliographicCitation.journaltitle | Marine Drugs | none |
dcterms.bibliographicCitation.volume | 19 | none |
dcterms.bibliographicCitation.issue | 5 | none |
dcterms.bibliographicCitation.articlenumber | 241 | none |
dcterms.bibliographicCitation.originalpublishername | MDPI | none |
dcterms.bibliographicCitation.originalpublisherplace | Basel | none |
bua.import.affiliation | Khalifa, Shaden A. M.; Department of Molecular Biosciences, Wenner-Gren Institute, Stockholm University, SE-106 91 Stockholm, Sweden, shaden.khalifa@su.se | none |
bua.import.affiliation | Shedid, Eslam S.; Department of Chemistry, Faculty of Science, Menoufia University, Shebin El-Kom 32512, Egypt, eslamshaker566@yahoo.com | none |
bua.import.affiliation | Saied, Essa M.; Chemistry Department, Faculty of Science, Suez Canal University, Ismailia 41522, Egypt, saiedess@hu-berlin.de; Institut für Chemie, Humboldt-Universität zu Berlin, Brook-Taylor-Straße 2, 12489 Berlin, Germany, saiedess@hu-berlin.de | none |
bua.import.affiliation | Jassbi, Amir Reza; Medicinal and Natural Products Chemistry Research Center, Shiraz University of Medical Sciences, Shiraz 71348-53734, Iran, jassbiar@sums.ac.ir | none |
bua.import.affiliation | Jamebozorgi, Fatemeh H.; Medicinal and Natural Products Chemistry Research Center, Shiraz University of Medical Sciences, Shiraz 71348-53734, Iran, fh_esfand@yahoo.com | none |
bua.import.affiliation | Rateb, Mostafa E.; School of Computing, Engineering & Physical Sciences, University of the West of Scotland, High Street, Paisley PA1 2BE, UK, mostafa.rateb@uws.ac.uk | none |
bua.import.affiliation | Du, Ming; School of Food Science and Technology, National Engineering Research Center of Seafood, Dalian Polytechnic University, Dalian 116034, China, duming@dlpu.edu.cn | none |
bua.import.affiliation | Abdel-Daim, Mohamed M.; Pharmacology Department, Faculty of Veterinary Medicine, Suez Canal University, Ismailia 41522, Egypt, abdeldaim.m@vet.suez.edu.eg | none |
bua.import.affiliation | Kai, Guo-Yin; Laboratory of Medicinal Plant Biotechnology, College of Pharmacy, Zhejiang Chinese Medical University, Hangzhou 311402, China, kaiguoyin@zcmu.edu.cn | none |
bua.import.affiliation | Al-Hammady, Montaser A. M.; National Institute of Oceanography & Fisheries, NIOF, Cairo 11516, Egypt, Coralreef_niof1@yahoo.com | none |
bua.import.affiliation | Xiao, Jianbo; Institute of Food Safety and Nutrition, Jinan University, Guangzhou 510632, China, jianboxiao@jnu.edu.cn | none |
bua.import.affiliation | Guo, Zhiming; School of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China, guozhiming@ujs.edu.cn | none |
bua.import.affiliation | El-Seedi, Hesham R.; Department of Chemistry, Faculty of Science, Menoufia University, Shebin El-Kom 32512, Egypt, hesham.el-seedi@farmbio.uu.se International Research Center for Food Nutrition and Safety, Jiangsu University, Zhenjiang 212013, China, hesham.el-seedi@farmbio.uu.se; Pharmacognosy Group, Department of Pharmaceutical Biosciences, Uppsala University, Biomedical Centre, P.O. Box 574, SE-751 23 Uppsala, Sweden, hesham.el-seedi@farmbio.uu.se | none |
bua.department | Mathematisch-Naturwissenschaftliche Fakultät | none |