Browsing Artikel und Monographien by Author "Dahmen, Uta"

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2017-11-14Zeitschriftenartikel

Computational Modeling in Liver Surgery

Christ, Bruno; Dahmen, Uta; Herrmann, Karl-Heinz; König, Matthias; Reichenbach, Jürgen R.; Ricken, Tim; Schleicher, Jana; Schwen, Lars Ole; Vlaic, Sebastian; Waschinsky, Navina

The need for extended liver resection is increasing due to the growing incidence of liver tumors in aging societies. Individualized surgical planning is the key for identifying the optimal resection strategy and to minimize ...
2024-05-16Zeitschriftenartikel

Cross-species variability in lobular geometry and cytochrome P450 hepatic zonation: insights into CYP1A2, CYP2D6, CYP2E1 and CYP3A4

Albadry, Mohamed; Küttner, Jonas; Grzegorzewski, Jan; Dirsch, Olaf; Kindler, Eva; Klopfleisch, Robert; Liska, Vaclav; Moulisova, Vladimira; Nickel, Sandra; Palek, Richard; Rosendorf, Jachym; Saalfeld, Sylvia; Settmacher, Utz; Tautenhahn, Hans-Michael; König, Matthias;

There is a lack of systematic research exploring cross-species variation in liver lobular geometry and zonation patterns of critical drug-metabolizing enzymes, a knowledge gap essential for translational studies. This study ...
2021-11-18Zeitschriftenartikel

Hepatectomy-Induced Alterations in Hepatic Perfusion and Function - Toward Multi-Scale Computational Modeling for a Better Prediction of Post-hepatectomy Liver Function

Christ, Bruno; Collatz, Maximilian; Dahmen, Uta; Herrmann, Karl-Heinz; Höpfl, Sebastian; König, Matthias; Lambers, Lena; Marz, Manja; Meyer, Daria; Radde, Nicole; Reichenbach, Jürgen R.; Ricken, Tim; Tautenhahn, Hans-Michael

Liver resection causes marked perfusion alterations in the liver remnant both on the organ scale (vascular anatomy) and on the microscale (sinusoidal blood flow on tissue level). These changes in perfusion affect hepatic ...