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2020-09-01Zeitschriftenartikel DOI: 10.1177/1550059419899324
P50, N100, and P200 Sensory Gating in Panic Disorder
dc.contributor.authorThoma, Lars
dc.contributor.authorRentzsch, Johannes
dc.contributor.authorGaudlitz, Katharina
dc.contributor.authorTänzer, Nicole
dc.contributor.authorGallinat, Jürgen
dc.contributor.authorKathmann, Norbert
dc.contributor.authorStröhle, Andreas
dc.contributor.authorPlag, Jens
dc.date.accessioned2022-06-23T11:39:48Z
dc.date.available2022-06-23T11:39:48Z
dc.date.issued2020-09-01none
dc.date.updated2020-07-23T22:01:40Z
dc.identifier.issn1550-0594
dc.identifier.urihttp://edoc.hu-berlin.de/18452/25490
dc.description.abstractPanic disorder (PD) has been linked to abnormalities in information processing. However, only little evidence has been published for sensory gating in PD. Sensory gating describes the brain’s ability to exclude stimuli of low relevance from higher level information processing, thereby sustaining efficient cognitive processing. Deficits in sensory gating have been associated with various psychiatric conditions, most prominently schizophrenia. In this case-control event-related potential study, we tested 32 patients with PD and 39 healthy controls in a double click paradigm. Both groups were compared with regard to pre-attentive (P50), early-attentive (N100), and late-attentive (P200) sensory gating indices. Contrary to a hypothesized deficit, PD patients and healthy controls showed no differences in P50, N100 and P200 values. These results suggest that sensory gating seems to be functional across the pre-attentive, early-attentive, and late-attentive time span in this clinical population. Given this consistency across auditory sensory gating indices, further research aiming to clarify information processing deficits in PD should focus on other neurophysiological markers to investigate information processing deficits in PD (eg, P300, error-related negativity or mismatch negativity).eng
dc.language.isoengnone
dc.publisherHumboldt-Universität zu Berlin
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/
dc.subjectpanic disordereng
dc.subjectsensory gatingeng
dc.subjectamplitude suppressioneng
dc.subjectP50, N100, and P200eng
dc.subjectelectroencephalography (EEG)eng
dc.subjectpre-, early-, and late-attentive information processingeng
dc.subjectanxiety disorderseng
dc.subject.ddc610 Medizin und Gesundheitnone
dc.titleP50, N100, and P200 Sensory Gating in Panic Disordernone
dc.typearticle
dc.identifier.urnurn:nbn:de:kobv:11-110-18452/25490-4
dc.identifier.doi10.1177/1550059419899324none
dc.identifier.doihttp://dx.doi.org/10.18452/24825
dc.type.versionpublishedVersionnone
local.edoc.container-titleClinical EEG and Neurosciencenone
local.edoc.pages8none
local.edoc.anmerkungThis publication is with permission of the rights owner freely accessible due to an alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.none
local.edoc.type-nameZeitschriftenartikel
local.edoc.institutionLebenswissenschaftliche Fakultätnone
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-publisher-nameSAGE Publicationsnone
local.edoc.container-publisher-placeLondonnone
local.edoc.container-volume51none
local.edoc.container-issue5none
local.edoc.container-firstpage317none
local.edoc.container-lastpage324none
dc.description.versionPeer Reviewednone
dc.identifier.eissn2169-5202

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