2023-04-27Zeitschriftenartikel
Discovery of the Lanthipeptide Curvocidin and Structural Insights into its Trifunctional Synthetase CuvL
Sigurdsson, Arnar; Martins, Berta M.; Düttmann, Simon A.; Jasyk, Martin; Dimos‐Röhl, Benjamin; Schöpf, Felix; Gemander, Manuel; Knittel, Caroline H.; Schnegotzki, Romina; Schmid, Bianca; Kosol, Simone; Pommerening, Lea; Gonzáles‐Viegaz, María; Seidel, Maria; Hügelland, Manuela;
Lanthipeptides are ribosomally-synthesized natural products from bacteria featuring stable thioether-crosslinks and various bioactivities. Herein, we report on a new clade of tricyclic class-IV lanthipeptides with curvocidin ...